Which of the following sexually transmitted infections results in a chronic condition even when treated medically?

Genital herpes is the sexually transmitted infection that leads to a chronic condition, even when treated medically. This is because, while antiviral medications can manage outbreaks and reduce the severity of symptoms, they do not eliminate the virus from the body. The herpes simplex virus (HSV), which causes genital herpes, resides in the nervous system and can remain dormant for long periods. Throughout a person's life, the virus can reactivate, leading to recurrent outbreaks and associated discomfort.

In contrast, other sexually transmitted infections such as gonorrhea, syphilis, and chlamydia are typically treatable and resolvable with appropriate antibiotic therapy. Once these bacterial infections are successfully treated, they do not cause chronic health issues. Therefore, genital herpes is unique among the listed infections for its ability to become a lifelong, chronic condition.